Welcome to the Lee Research Laboratory

We are engaged in translational research to investigate cellular and molecular mechanisms involved in acute and chronic brain injury, with a focus on Ischemic stroke and Alzheimer’s disease.  An additional focus of the lab is neuroplasticity and brain repair after stroke.  A major motivation of the lab is to identify strategies and targets for mitigating brain injury and enhancing brain repair after injury.  The lab utilizes cutting-edge approaches in molecular biology, mouse genetics, neuroimaging (microscopic and mesoscopic), advanced image analysis (data-driven and machine learning approaches), advanced statistical approaches, and genomics.  A unique aspect of the Lee lab is its bi-directional approach to translational research—taking advantage of both traditional forward-translational (bench-to-bedside) as well as reverse-translational (bedside-to-bench) approaches.  Thus, the lab is facile in both human clinical studies, as well as studies utilizing cellular and animal models of disease.