Bridging science and care to uncover brain healing and boost recovery
Our lab investigates the cellular and molecular mechanisms behind brain injuries such as stroke and Alzheimer’s disease. Our mission is to uncover how the brain heals itself and to develop therapies that enhance recovery and repair.
We use cutting-edge tools in:
Our bi-directional translational approach bridges clinical trials and lab discoveries, ensuring our work impacts real-world patient care.
Jin-Moo Lee, MD, PhD, is an internationally recognized leader in stroke and cerebrovascular research and serves as head of the Department of Neurology and the Andrew B. and Gretchen P. Jones Professor of Neurology at WashU Medicine. He also holds appointments in radiology and biomedical engineering and co-directs the Stroke and Cerebrovascular Center at Barnes-Jewish Hospital and WashU Medicie. His research focuses on the cellular and molecular mechanisms of brain injury and recovery, including neuroplasticity after stroke, amyloid precursor protein processing in Alzheimer’s disease and the pathogenesis of cerebral small vessel disease.
Lee has been continuously funded by the NIH for more than two decades and currently holds a Javits Neuroscience Investigator Award. He leads the GENESIS study, chairs the International Stroke Genetics Consortium, and has spearheaded regional initiatives to improve stroke care, including one of the fastest “door-to-needle” response systems in the country. A highly collaborative scientist and mentor, he has received numerous awards for research and teaching while advancing discoveries that bridge basic science and clinical care.
National Institutes of Health (NIH)
Barnes–Jewish Foundation
Alzheimer’s Disease and Related Disorders Association
